Search results for "methods [Gene Expression Profiling]"

showing 10 items of 838 documents

IceCube-Gen2: The Window to the Extreme Universe

2020

The observation of electromagnetic radiation from radio to $\gamma$-ray wavelengths has provided a wealth of information about the universe. However, at PeV (10$^{15}$ eV) energies and above, most of the universe is impenetrable to photons. New messengers, namely cosmic neutrinos, are needed to explore the most extreme environments of the universe where black holes, neutron stars, and stellar explosions transform gravitational energy into non-thermal cosmic rays. The discovery of cosmic neutrinos with IceCube has opened this new window on the universe. In this white paper, we present an overview of a next-generation instrument, IceCube-Gen2, which will sharpen our understanding of the proce…

PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)astro-ph.HENuclear and High Energy PhysicsActive galactic nucleus010308 nuclear & particles physicsHigh-energy astronomyGravitational wavemedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyFOS: Physical sciencesCosmic ray01 natural sciencesUniverseNeutron star0103 physical sciencesNeutrinoNeutrino astronomyAstrophysics - High Energy Astrophysical Phenomena010303 astronomy & astrophysicsmedia_common
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The extragalactic gamma-ray sky : a view on the most powerful phenomena in the universe

2016

The gamma-ray sky provides a look into the most energetic and violent processes of the universe. In the last years, gamma-ray satellites are scanning the sky for understanding the physics governing the gamma-ray emission. A wealth of information on the physics of the gamma-ray sky has been obtained by gamma-ray satellites orbiting around the Earth. So far, roughly three thousands sources have been detected in gamma-rays, and this number is going to increase as the gamma-ray missions continue to survey the sky. The high energy sky is dominated by extragalactic objects. A large fraction of the detected sources has no obvious counterpart in catalogs at other wavelengths, leaving their nature u…

PhysicsHigh energyMultidisciplinarymedia_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaGamma rayAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyAstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsHistory and Philosophy of ScienceSkyAstrophysics::Galaxy Astrophysicsmedia_common
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Non-thermal processes in coronae and beyond

2013

This contribution summarizes the splinter session “Non-thermal processes in coronae and beyond” held at the Cool Stars 17 workshop in Barcelona in 2012. It covers new developments in high energy non-thermal effects in the Earth's exosphere, solar and stellar flares, the diffuse emission in star forming regions and reviews the state and the challenges of the underlying atomic databases. (© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

PhysicsHigh energyStarsSolar flareSpace and Planetary ScienceThermalAstronomyAstronomy and AstrophysicsMethods laboratoryExosphereAtomic dataAstronomische Nachrichten
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Summary of Working Group 4: High Energy Neutrino Telescopes

2007

The field of high-energy neutrino astronomy is rapidly developing. A number of new experiments are currently being deployed and developed. Additionally, the recent successes of TeV gamma-ray astronomy have exciting implications for future neutrino telescopes. Here we will summarize these and other issues as they were discussed in the TeV II workshop's neutrino astronomy working group.

PhysicsHistoryHigh energyHigh-energy astronomyAstrophysics::High Energy Astrophysical PhenomenaSolar neutrinoHigh Energy Physics::PhenomenologyAstrophysics::Instrumentation and Methods for AstrophysicsAstronomyAstrophysicsSolar neutrino problemComputer Science ApplicationsEducationNeutrino detectorHigh Energy Physics::ExperimentNeutrinoNeutrino astronomyLeptonJournal of Physics: Conference Series
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Underground cosmic-ray experiment EMMA

2013

EMMA (Experiment with MultiMuon Array) is a new approach to study the composition of cosmic rays at the knee region (1 − 10 PeV). The array will measure the multiplicity and lateral distribution of the high-energy muon component of an air shower and its arrival direction on an event-by-event basis. The array operates in the Pyh¨asalmi Mine, Finland, at a depth of 75 metres (or 210 m.w.e) corresponding to the cut-off energy of approximately 50 GeV for vertical muons. The data recording with a partial array has started and preliminary results of the first test runs are presented. nonPeerReviewed

PhysicsHistoryMuonPhysics::Instrumentation and DetectorsAstrophysics::High Energy Astrophysical PhenomenaAstrophysics::Instrumentation and Methods for AstrophysicsCosmic rayKnee regionComputer Science ApplicationsEducationNuclear physicsAstrohiukkasfysiikkaAir showerData recordingAstroparticle physics
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Numerical viscosity in simulations of the two-dimensional Kelvin-Helmholtz instability

2020

The Kelvin-Helmholtz instability serves as a simple, well-defined setup for assessing the accuracy of different numerical methods for solving the equations of hydrodynamics. We use it to extend our previous analysis of the convergence and the numerical dissipation in models of the propagation of waves and in the tearing-mode instability in magnetohydrodynamic models. To this end, we perform two-dimensional simulations with and without explicit physical viscosity at different resolutions. A comparison of the growth of the modes excited by our initial perturbations allows us to estimate the effective numerical viscosity of two spatial reconstruction schemes (fifth-order monotonicity preservin…

PhysicsHistoryNumerical analysisFOS: Physical sciences010103 numerical & computational mathematicsMechanicsComputational Physics (physics.comp-ph)Dissipation01 natural sciencesInstabilityComputer Science ApplicationsEducationPiecewise linear functionViscositySimple (abstract algebra)0103 physical sciencesConvergence (routing)Magnetohydrodynamic drive0101 mathematicsAstrophysics - Instrumentation and Methods for AstrophysicsInstrumentation and Methods for Astrophysics (astro-ph.IM)Physics - Computational Physics010303 astronomy & astrophysicsJournal of Physics: Conference Series
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Study of the Planacon XP85012 photomultiplier characteristics for its use in a Cherenkov detector

2016

Main properties of the multi-anode microchannel plate photomultiplier to be used in a Cherenkov detector are discussed. The laboratory test results obtained using irradiation of the MCP-PMT photocathode by picosecond optical laser pulses with different intensities (from single photon regime to the PMT saturation conditions) are presented. peerReviewed

PhysicsHistoryPhotomultiplierPhotonPhysics::Instrumentation and DetectorsCherenkov detectorbusiness.industryPhysics::Medical PhysicsAstrophysics::Instrumentation and Methods for AstrophysicsPhysics::OpticsLaserPhotocathodeComputer Science ApplicationsEducationlaw.inventionOpticslawPicosecondMicrochannel plate detectorIrradiationbusinessCherenkov detectorJournal of Physics: Conference Series
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Performance study of the fast timing Cherenkov detector based on a microchannel plate PMT

2017

Prototype of the fast timing Cherenkov detector, applicable in high-energy collider experiments, has been developed basing on the modified Planacon XP85012 MCP-PMT and fused silica radiators. We present the reasons and description of the MCP-PMT modification, timing and amplitude characteristics of the prototype including the summary of the detector's response on particle hits at oblique angles and MCP-PMT performance at high illumination rates.

PhysicsHistoryPhotomultiplierPhysics::Instrumentation and Detectors010308 nuclear & particles physicsbusiness.industryCherenkov detectorQuantitative Biology::Tissues and OrgansDetectorAstrophysics::Instrumentation and Methods for Astrophysics01 natural sciencesParticle detectorComputer Science ApplicationsEducationlaw.inventionOpticslaw0103 physical sciencesScintillation counterMeasuring instrumentMicrochannel plate detector010306 general physicsbusinessColliderJournal of Physics: Conference Series
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Determination of IBIS mask transmission matrix

2005

The high-angular resolution imager IBIS is one of the two main instruments aboard the ESA INTEGRAL satellite launched in October 2002. IBIS uses coded aperture mask technique in order to provide the required imaging capabilities for energies between 15 and 10 MeV.The precise knowledge of the coded mask response function critically determine the IBIS imaging performances. In this paper, we present a general description of the IBIS coded mask design together with its main features. Transparency and homogeneity values of the IBIS mask flight model from our laboratory measurements are presented with indication of the instrumental set-up used and accuracy achieved. Mask transmission as a functio…

PhysicsIbisNuclear and High Energy PhysicsPhotonbiologybusiness.industryAstrophysics::High Energy Astrophysical PhenomenaMonte Carlo methodAstrophysics::Instrumentation and Methods for Astrophysicsbiology.organism_classificationIntegrated circuit layoutOpticsTransmission (telecommunications)SatelliteCoded aperturebusinessInstrumentationEnergy (signal processing)Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
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The European Photon Imaging Camera on XMM-Newton: The MOS Cameras

2000

The EPIC focal plane imaging spectrometers on XMM-Newton use CCDs to record the images and spectra of celestial X-ray sources focused by the three X-ray mirrors. There is one camera at the focus of each mirror; two of the cameras contain seven MOS CCDs, while the third uses twelve PN CCDs, defining a circular field of view of 30 arcmin diameter in each case. The CCDs were specially developed for EPIC, and combine high quality imaging with spectral resolution close to the Fano limit. A filter wheel carrying three kinds of X-ray transparent light blocking filter, a fully closed, and a fully open position, is fitted to each EPIC instrument. The CCDs are cooled passively and are under full clos…

PhysicsInstrumentation: detectorPhotonSpectrometerbusiness.industryDynamic rangeAstrophysics::High Energy Astrophysical PhenomenaAstrophysics (astro-ph)Astrophysics::Instrumentation and Methods for AstrophysicsFOS: Physical sciencesAstronomy and AstrophysicsField of viewAstrophysicsAstrophysicsX-rays: generalOpticsCardinal pointSpace and Planetary ScienceCalibrationSpectral resolutionbusinessFocus (optics)
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